BRAF vs RAS oncogenes: are mutations of the same pathway equal? differential signalling and therapeutic implications

As the increased knowledge of tumour heterogeneity and genetic alterations progresses, it exemplifies the need for further personalized medicine in modern cancer management. Here, the similarities but also the differential effects of RAS and BRAF oncogenic signalling are examined and further implica...

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Detalles Bibliográficos
Autores principales: Oikonomou, Eftychia, Koustas, Evangelos, Goulielmaki, Maria, Pintzas, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322985/
https://www.ncbi.nlm.nih.gov/pubmed/25361007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322985/
https://www.ncbi.nlm.nih.gov/pubmed/25361007

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