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Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

The role of endoplasmic reticulum (ER) stress in cancer has been studied in detail, and ER stress is known to increase tumor cell apoptosis, and thus, reduce tumor growth. However, in our study, persistent ER stress induced by multiple administrations of low-dose thapsigargin (Tg) accelerated tumor...

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Detalles Bibliográficos
Autores principales: Lee, Bo-Ra, Chang, Sun-Young, Hong, Eun-Hye, Kwon, Bo-Eun, Kim, Hong Min, Kim, Yeon-Jeong, Lee, Jongkook, Cho, Hyun-Jong, Cheon, Jae-Hee, Ko, Hyun-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322987/
https://www.ncbi.nlm.nih.gov/pubmed/25514597