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Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells

In this study, we identified ret finger protein-like 3 (RFPL3) as a hTERT promoter binding protein in lung cancer cells. The high hTERT promoter-binding activity of RFPL3 was detected in lung cancer cells compared to normal cells. Chromatin immunoprecipitation confirmed RFPL3 as a tumor-specific hTE...

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Detalles Bibliográficos
Autores principales: Chen, Wangbing, Lu, Jianjun, Qin, Yu, Wang, Jingshu, Tian, Yun, Shi, Dingbo, Wang, Shusen, Xiao, Yao, Dai, Meng, Liu, Lu, Wei, Guo, Wu, Taihua, Jin, Bilian, Xiao, Xiangsheng, Kang, Tie-Bang, Huang, Wenlin, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322990/
https://www.ncbi.nlm.nih.gov/pubmed/25481043