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Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells

Alcohol consumption in women has been associated with an increased risk of breast cancer, particular in estrogen receptor positive (ER+) cases. Deregulation of RNA polymerase III-dependent (Pol III) transcription enhances cellular tRNAs and 5S rRNA production, leading to an increase in translational...

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Detalles Bibliográficos
Autores principales: Zhong, Qian, Shi, Ganggang, Zhang, Qingsong, Lu, Lei, Levy, Daniel, Zhong, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322994/
https://www.ncbi.nlm.nih.gov/pubmed/25400119