Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets

Triple-negative breast cancer (TNBC) accounts for approximately 15–20% of all breast cancer (BC) cases and contributes disproportionately to BC mortality. TAZ, a key transducer of the Hippo pathway, has recently been demonstrated to confer breast cancer stem cell (CSC) traits. However, TAZ target ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Frangou, Costa, Li, Ying-Wei, Shen, He, Yang, Nuo, Wilson, Kayla E., Blijlevens, Maxime, Guo, Jin, Nowak, Norma J., Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323005/
https://www.ncbi.nlm.nih.gov/pubmed/25361000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323005/
https://www.ncbi.nlm.nih.gov/pubmed/25361000

Ejemplares similares