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Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells

Higher rate of glycolysis has been long observed in cancer cells, as a vital enzyme in glycolysis, lactate dehydrogenase A (LDH-A) has been shown with great potential as an anti-cancer target. Accumulating evidence indicates that inhibition of LDH-A induces apoptosis mediated by oxidative stress in...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Su, Dan, Zhao, Lin, Zhang, Dan, Xu, Jiaying, Wan, Jianmei, Fan, Saijun, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323009/
https://www.ncbi.nlm.nih.gov/pubmed/25361010