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Genetic basis for the lack of N-glycolylneuraminic acid expression in human tissues and its implication to human evolution
Sialic acid is a family of acidic monosaccharides and consists of over 30 derivatives. Two major derivatives are N-acetylneuraminic acid (NeuAc) and N-glycolylneuraminic acid (NeuGc), and the hydroxylation of CMP-NeuAc is the rate limiting reaction for the production of NeuGc. The hydroxylation was...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japan Academy
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323044/ https://www.ncbi.nlm.nih.gov/pubmed/25873750 |