Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner

BACKGROUND: Hepatitis C virus (HCV) infection was recently recognized as an independent risk factor for insulin resistance (IR), the onset phase of type 2 diabetes mellitus (T2DM). Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) negatively regulates PI3K/Akt signaling pathway, which i...

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Detalles Bibliográficos
Autores principales: Gao, Ting-ting, Qin, Zhao-ling, Ren, Hao, Zhao, Ping, Qi, Zhong-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323155/
https://www.ncbi.nlm.nih.gov/pubmed/25645159
http://dx.doi.org/10.1186/s12985-015-0241-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323155/
https://www.ncbi.nlm.nih.gov/pubmed/25645159
http://dx.doi.org/10.1186/s12985-015-0241-4

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