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Correlation of Perfusion MRI and (18)F-FDG PET Imaging Biomarkers for Monitoring Regorafenib Therapy in Experimental Colon Carcinomas with Immunohistochemical Validation

OBJECTIVES: To investigate a multimodal, multiparametric perfusion MRI / (18)F-fluoro-deoxyglucose-((18)F-FDG)-PET imaging protocol for monitoring regorafenib therapy effects on experimental colorectal adenocarcinomas in rats with immunohistochemical validation. MATERIALS AND METHODS: Human colorect...

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Detalles Bibliográficos
Autores principales: Eschbach, Ralf S., Fendler, Wolfgang P., Kazmierczak, Philipp M., Hacker, Marcus, Rominger, Axel, Carlsen, Janette, Hirner-Eppeneder, Heidrun, Schuster, Jessica, Moser, Matthias, Havla, Lukas, Schneider, Moritz J., Ingrisch, Michael, Spaeth, Lukas, Reiser, Maximilian F., Nikolaou, Konstantin, Cyran, Clemens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323201/
https://www.ncbi.nlm.nih.gov/pubmed/25668193
http://dx.doi.org/10.1371/journal.pone.0115543