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Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

Intervertebral disc (IVD) degeneration and pathological spinal changes are major causes of back pain, which is the top cause of global disability. Obese and diabetic individuals are at increased risk for back pain and musculoskeletal complications. Modern diets contain high levels of advanced glycat...

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Detalles Bibliográficos
Autores principales: Illien-Jünger, Svenja, Lu, Young, Qureshi, Sheeraz A., Hecht, Andrew C., Cai, Weijing, Vlassara, Helen, Striker, Gary E., Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323205/
https://www.ncbi.nlm.nih.gov/pubmed/25668621
http://dx.doi.org/10.1371/journal.pone.0116625