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Patient-derived xenograft models of breast cancer and their predictive power

Despite advances in the treatment of patients with early and metastatic breast cancer, mortality remains high due to intrinsic or acquired resistance to therapy. Increased understanding of the genomic landscape through massively parallel sequencing has revealed somatic mutations common to specific s...

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Detalles Bibliográficos
Autores principales: Whittle, James R, Lewis, Michael T, Lindeman, Geoffrey J, Visvader, Jane E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323263/
https://www.ncbi.nlm.nih.gov/pubmed/25849559
http://dx.doi.org/10.1186/s13058-015-0523-1