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Reducing lactate secretion by ldhA Deletion in L-glutamate- producing strain Corynebacterium glutamicum GDK-9

L-lactate is one of main byproducts excreted in to the fermentation medium. To improve L-glutamate production and reduce L-lactate accumulation, L-lactate dehydrogenase-encoding gene ldhA was knocked out from L-glutamate producing strain Corynebacterium glutamicum GDK-9, designated GDK-9ΔldhA. GDK-9...

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Detalles Bibliográficos
Autores principales: Zhang, Dalong, Guan, Dan, Liang, Jingbo, Guo, Chunqian, Xie, Xixian, Zhang, Chenglin, Xu, Qingyang, Chen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323326/
https://www.ncbi.nlm.nih.gov/pubmed/25763057