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NADPH Oxidase-Dependent Production of Reactive Oxygen Species Induces Endoplasmatic Reticulum Stress in Neutrophil-Like HL60 Cells

Reactive oxygen species (ROS) primarily produced via NADPH oxidase play an important role for killing microorganisms in neutrophils. In this study we examined if ROS production in Human promyelocytic leukemia cells (HL60) differentiated into neutrophil-like cells (dHL60) induces ER stress and activa...

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Detalles Bibliográficos
Autores principales: Kuwabara, Wilson Mitsuo Tatagiba, Zhang, Liling, Schuiki, Irmgard, Curi, Rui, Volchuk, Allen, Alba-Loureiro, Tatiana Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323339/
https://www.ncbi.nlm.nih.gov/pubmed/25668518
http://dx.doi.org/10.1371/journal.pone.0116410