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Weight Loss by Ppc-1, a Novel Small Molecule Mitochondrial Uncoupler Derived from Slime Mold

Mitochondria play a key role in diverse processes including ATP synthesis and apoptosis. Mitochondrial function can be studied using inhibitors of respiration, and new agents are valuable for discovering novel mechanisms involved in mitochondrial regulation. Here, we screened small molecules derived...

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Detalles Bibliográficos
Autores principales: Suzuki, Toshiyuki, Kikuchi, Haruhisa, Ogura, Masato, Homma, Miwako K., Oshima, Yoshiteru, Homma, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323345/
https://www.ncbi.nlm.nih.gov/pubmed/25668511
http://dx.doi.org/10.1371/journal.pone.0117088