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Solid-Phase Synthesis and Hybrization Behavior of Partially 2′/3′-O-Acetylated RNA Oligonucleotides

[Image: see text] Synthesis of partially 2′/3′-O-acetylated oligoribonucleotides has been accomplished by using a 2′/3′-O-acetyl orthogonal protecting group strategy in which non-nucleophilic strong-base (DBU) labile nucleobase protecting groups and a UV-light cleavable linker were used. Strong-base...

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Detalles Bibliográficos
Autores principales: Xu, Jianfeng, Duffy, Colm D., Chan, Christopher K. W., Sutherland, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323357/
https://www.ncbi.nlm.nih.gov/pubmed/24666354
http://dx.doi.org/10.1021/jo5002824