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Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria

Antibiotic resistance carries a fitness cost that could potentially limit the spread of resistance in bacterial pathogens. In spite of this cost, a large number of experimental evolution studies have found that resistance is stably maintained in the absence of antibiotics as a result of compensatory...

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Detalles Bibliográficos
Autores principales: MacLean, R. Craig, Vogwill, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323496/
https://www.ncbi.nlm.nih.gov/pubmed/25535278
http://dx.doi.org/10.1093/emph/eou032