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Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria
Antibiotic resistance carries a fitness cost that could potentially limit the spread of resistance in bacterial pathogens. In spite of this cost, a large number of experimental evolution studies have found that resistance is stably maintained in the absence of antibiotics as a result of compensatory...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323496/ https://www.ncbi.nlm.nih.gov/pubmed/25535278 http://dx.doi.org/10.1093/emph/eou032 |