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Virological and Preclinical Characterization of a Dendritic Cell Targeting, Integration-deficient Lentiviral Vector for Cancer Immunotherapy

Dendritic cells (DCs) are essential antigen-presenting cells for the initiation of cytotoxic T-cell responses and therefore attractive targets for cancer immunotherapy. We have developed an integration-deficient lentiviral vector termed ID-VP02 that is designed to deliver antigen-encoding nucleic ac...

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Detalles Bibliográficos
Autores principales: Odegard, Jared M., Kelley-Clarke, Brenna, Tareen, Semih U., Campbell, David J., Flynn, Patrick A., Nicolai, Christopher J., Slough, Megan M., Vin, Chintan D., McGowan, Patrick J., Nelson, Lisa T., ter Meulen, Jan, Dubensky, Thomas W., Robbins, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323576/
https://www.ncbi.nlm.nih.gov/pubmed/25658613
http://dx.doi.org/10.1097/CJI.0000000000000067