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Single Intracoronary Injection of Encapsulated Antagomir‐92a Promotes Angiogenesis and Prevents Adverse Infarct Remodeling

BACKGROUND: Small and large preclinical animal models have shown that antagomir‐92a‐based therapy reduces early postischemic loss of function, but its effect on postinfarction remodeling is not known. In addition, the reported remote miR‐92a inhibition in noncardiac organs prevents the translation o...

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Detalles Bibliográficos
Autores principales: Bellera, Neus, Barba, Ignasi, Rodriguez‐Sinovas, Antonio, Ferret, Eulalia, Asín, Miguel Angel, Gonzalez‐Alujas, MªTeresa, Pérez‐Rodon, Jordi, Esteves, Marielle, Fonseca, Carla, Toran, Nuria, Garcia del Blanco, Bruno, Pérez, Amadeo, Garcia‐Dorado, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323815/
https://www.ncbi.nlm.nih.gov/pubmed/25240056
http://dx.doi.org/10.1161/JAHA.114.000946