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FoxO3 is a negative regulator of primary CD8(+) T cell expansion but not of memory formation

The generation of CD8(+) T cells by vaccination represents an important goal for protective immunity to infectious pathogens. It is thus of utmost importance to understand the mechanisms involved in the generation of optimal CD8(+) T cell responses. The forkhead box O (FoxO) family of transcription...

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Detalles Bibliográficos
Autores principales: Togher, Susan, Larange, Alexandre, Schoenberger, Stephen P., Feau, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324096/
https://www.ncbi.nlm.nih.gov/pubmed/25245112
http://dx.doi.org/10.1038/icb.2014.78