Self-assembled micelles of amphiphilic PEGylated rapamycin for loading paclitaxel and resisting multidrug resistant cancer cells

Self-assembled micelles of amphiphilic PEG–rapamycin conjugates loaded with paclitaxel have been developed for co-delivery and simultaneous intracellular release of paclitaxel and rapamycin, bypassing the cancer cell drug resistant mechanism and maximising the synergy of dual-drug combinational ther...

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Detalles Bibliográficos
Autores principales: Tian, Wei, Liu, Jieying, Guo, Yuan, Shen, Yuanyuan, Zhou, Dejian, Guo, Shengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324122/
https://www.ncbi.nlm.nih.gov/pubmed/25717377
http://dx.doi.org/10.1039/c4tb01633e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324122/
https://www.ncbi.nlm.nih.gov/pubmed/25717377
http://dx.doi.org/10.1039/c4tb01633e

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