Distinct action of the α-glucosidase inhibitor miglitol on SGLT3, enteroendocrine cells, and GLP1 secretion

Oral ingestion of carbohydrate triggers glucagon-like peptide 1 (GLP1) secretion, but the molecular mechanism remains elusive. By measuring GLP1 concentrations in murine portal vein, we found that the ATP-sensitive K(+) (K(ATP)) channel is not essential for glucose-induced GLP1 secretion from entero...

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Detalles Bibliográficos
Autores principales: Lee, Eun Young, Kaneko, Shuji, Jutabha, Promsuk, Zhang, Xilin, Seino, Susumu, Jomori, Takahito, Anzai, Naohiko, Miki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324305/
https://www.ncbi.nlm.nih.gov/pubmed/25486965
http://dx.doi.org/10.1530/JOE-14-0555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324305/
https://www.ncbi.nlm.nih.gov/pubmed/25486965
http://dx.doi.org/10.1530/JOE-14-0555

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