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Inflammasome Activation Contributes to Interleukin-23 Production in Response to Clostridium difficile
Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate an ASC-con...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324312/ https://www.ncbi.nlm.nih.gov/pubmed/25626905 http://dx.doi.org/10.1128/mBio.02386-14 |