Selective Activation of M(4) Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

[Image: see text] Positive allosteric modulators (PAMs) of the M(4) muscarinic acetylcholine receptor (mAChR) represent a novel approach for the treatment of psychotic symptoms associated with schizophrenia and other neuropsychiatric disorders. We recently reported that the selective M(4) PAM VU0152...

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Detalles Bibliográficos
Autores principales: Bubser, Michael, Bridges, Thomas M., Dencker, Ditte, Gould, Robert W., Grannan, Michael, Noetzel, Meredith J., Lamsal, Atin, Niswender, Colleen M., Daniels, J. Scott, Poslusney, Michael S., Melancon, Bruce J., Tarr, James C., Byers, Frank W., Wess, Jürgen, Duggan, Mark E., Dunlop, John, Wood, Michael W., Brandon, Nicholas J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324418/
https://www.ncbi.nlm.nih.gov/pubmed/25137629
http://dx.doi.org/10.1021/cn500128b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324418/
https://www.ncbi.nlm.nih.gov/pubmed/25137629
http://dx.doi.org/10.1021/cn500128b

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