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Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer
BACKGROUND: Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR, CCND1) target genes and prognostic gene alterations (MYC) had not been systematically studied. METHODS: To study het...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324419/ https://www.ncbi.nlm.nih.gov/pubmed/25649416 http://dx.doi.org/10.1186/s12876-015-0231-4 |