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Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

[Image: see text] HERC2 is a large E3 ubiquitin ligase with multiple structural domains that has been implicated in an array of cellular processes. Mutations in HERC2 are linked to developmental delays and impairment caused by nervous system dysfunction, such as Angelman Syndrome and autism-spectrum...

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Detalles Bibliográficos
Autores principales: Galligan, Jeffrey T., Martinez-Noël, Gustavo, Arndt, Verena, Hayes, Sebastian, Chittenden, Thomas W., Harper, J. Wade, Howley, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324439/
https://www.ncbi.nlm.nih.gov/pubmed/25476789
http://dx.doi.org/10.1021/pr501005v