Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways

Lung cancer is the leading cause of cancer death worldwide. Recently, two plant-derived drugs triptolide (TP) and hydroxycamptothecin (HCPT) both have shown broad-spectrum anticancer activities. Our previous study documented that combination treatment with these two drugs acted more effectively than...

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Detalles Bibliográficos
Autores principales: MENG, GUANMIN, WANG, WEI, CHAI, KEQUN, YANG, SUWEN, LI, FANGQIONG, JIANG, KAI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324588/
https://www.ncbi.nlm.nih.gov/pubmed/25573072
http://dx.doi.org/10.3892/ijo.2015.2814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324588/
https://www.ncbi.nlm.nih.gov/pubmed/25573072
http://dx.doi.org/10.3892/ijo.2015.2814

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