The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial

OBJECTIVES: Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients under...

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Detalles Bibliográficos
Autores principales: Drury, Nigel E., Howell, Neil J., Calvert, Melanie J., Weber, Ralf J.M., Senanayake, Eshan L., Lewis, Michael E., Hyde, Jonathan A.J., Green, David H., Mascaro, Jorge G., Wilson, Ian C., Graham, Timothy R., Rooney, Stephen J., Viant, Mark R., Freemantle, Nick, Frenneaux, Michael P., Pagano, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Adult Cardiac
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324609/
https://www.ncbi.nlm.nih.gov/pubmed/24948413
http://dx.doi.org/10.1093/ejcts/ezu238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324609/
https://www.ncbi.nlm.nih.gov/pubmed/24948413
http://dx.doi.org/10.1093/ejcts/ezu238

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