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Effects of Low Doses of Pioglitazone on Resting-State Functional Connectivity in Conscious Rat Brain

Pioglitazone (PIO) is a peroxisome proliferator-activated receptor-γ (PPARγ) agonist in clinical use for treatment of type 2 diabetes (T2DM). Accumulating evidence suggests PPARγ agonists may be useful for treating or delaying the onset of Alzheimer’s disease (AD), possibly via actions on mitochondr...

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Detalles Bibliográficos
Autores principales: Crenshaw, Donna G., Asin, Karen, Gottschalk, William K., Liang, Zhifeng, Zhang, Nanyin, Roses, Allen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324644/
https://www.ncbi.nlm.nih.gov/pubmed/25671601
http://dx.doi.org/10.1371/journal.pone.0117973