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Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo

BACKGROUND: This study evaluates the time-dependent pro-inflammatory response of the model human lung epithelial cells (A549) to industrially relevant zinc oxide nanoparticles (ZnO NPs). In terms of toxicity, ZnO-NPs are categorised into the group of high toxicity nanomaterials. However information...

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Detalles Bibliográficos
Autores principales: Saptarshi, Shruti R, Feltis, Bryce N, Wright, Paul FA, Lopata, Andreas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324663/
https://www.ncbi.nlm.nih.gov/pubmed/25645871
http://dx.doi.org/10.1186/s12951-015-0067-7