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Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo
BACKGROUND: This study evaluates the time-dependent pro-inflammatory response of the model human lung epithelial cells (A549) to industrially relevant zinc oxide nanoparticles (ZnO NPs). In terms of toxicity, ZnO-NPs are categorised into the group of high toxicity nanomaterials. However information...
Autores principales: | Saptarshi, Shruti R, Feltis, Bryce N, Wright, Paul FA, Lopata, Andreas L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324663/ https://www.ncbi.nlm.nih.gov/pubmed/25645871 http://dx.doi.org/10.1186/s12951-015-0067-7 |
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