Targeted Protein Destabilization Reveals an Estrogen-mediated ER Stress Response

Accumulation of unfolded proteins within the endoplasmic reticulum (ER) of eukaryotic cells leads to an unfolded protein response (UPR) that either restores homeostasis or commits the cells to apoptosis. Tools traditionally used to study the UPR are pro-apoptotic and thus confound analysis of long-t...

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Detalles Bibliográficos
Autores principales: Raina, Kanak, Noblin, Devin J., Serebrenik, Yevgeniy V., Adams, Alison, Zhao, Connie, Crews, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324732/
https://www.ncbi.nlm.nih.gov/pubmed/25242550
http://dx.doi.org/10.1038/nchembio.1638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324732/
https://www.ncbi.nlm.nih.gov/pubmed/25242550
http://dx.doi.org/10.1038/nchembio.1638

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