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Low Mutational Burden of Eight Genes Involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 Pathways in Female Genital Tract Primary Melanomas

Mucosal melanomas exhibit discrete genetic features compared to cutaneous melanoma. Limited studies on gynecological melanomas revealed significant heterogeneity and low mutational burden. To gain further insight into their genetics and DNA repair efficiency, we systematically investigated the statu...

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Detalles Bibliográficos
Autores principales: Pappa, Kalliopi I., Vlachos, George D., Roubelakis, Maria, Vlachos, Dimitrios-Efthymios G., Kalafati, Theodora G., Loutradis, Dimitrios, Anagnou, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324736/
https://www.ncbi.nlm.nih.gov/pubmed/25695059
http://dx.doi.org/10.1155/2015/303791