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Randomized Phase III Trial of Adjuvant Chemotherapy with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of the Head and Neck (ACTS-HNC)

BACKGROUND: We conducted a phase III study to evaluate S-1 as compared with UFT as control in patients after curative therapy for stage III, IVA, or IVB squamous-cell carcinoma of the head and neck (SCCHN). PATIENTS AND METHODS: Patients were randomly assigned to the UFT group (300 or 400 mg day(-1)...

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Detalles Bibliográficos
Autores principales: Tsukahara, Kiyoaki, Kubota, Akira, Hasegawa, Yasuhisa, Takemura, Hideki, Terada, Tomonori, Taguchi, Takahide, Nagahara, Kunihiko, Nakatani, Hiroaki, Yoshino, Kunitoshi, Higaki, Yuichiro, Iwae, Shigemichi, Beppu, Takeshi, Hanamure, Yutaka, Tomita, Kichinobu, Kohno, Naoyuki, Kawabata, Kazuyoshi, Fukushima, Masanori, Teramukai, Satoshi, Fujii, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324826/
https://www.ncbi.nlm.nih.gov/pubmed/25671770
http://dx.doi.org/10.1371/journal.pone.0116965