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Anti-EGFR Antibody Reduces Lung Nodules by Inhibition of EGFR-Pathway in a Model of Lymphangioleiomyomatosis

EGFR belongs to the HER/ErbB family of tyrosine kinase receptors and its activation in cancer cells has been linked with increased proliferation, angiogenesis, and metastasis. Lymphangioleiomyomatosis (LAM) is a rare, low-grade neoplasm that occurs sporadically or in association with tuberous sclero...

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Detalles Bibliográficos
Autores principales: Lesma, Elena, Chiaramonte, Eloisa, Ancona, Silvia, Orpianesi, Emanuela, Di Giulio, Anna Maria, Gorio, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324894/
https://www.ncbi.nlm.nih.gov/pubmed/25699271
http://dx.doi.org/10.1155/2015/315240