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Ionizing radiation-induced XRCC4 phosphorylation is mediated through ATM in addition to DNA-PK

XRCC4 (X-ray cross-complementation group 4) is a protein associated with DNA ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end-joining. It has been shown that, in response to irradiation or treatment with DNA damaging agen...

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Detalles Bibliográficos
Autores principales: IMAMICHI, Shoji, SHARMA, Mukesh Kumar, KAMDAR, Radhika Pankaj, FUKUCHI, Mikoto, MATSUMOTO, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324928/
https://www.ncbi.nlm.nih.gov/pubmed/25391321
http://dx.doi.org/10.2183/pjab.90.365