The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells

Prolonged hyperglycemia is an important risk factor of the pathogenesis of diabetic retinopathy (DR). Extracellular matrix molecules, such as fibronectin, collagen IV, and laminin, are associated with fibrotic membranes. In this study, we investigated the expression of fibronectin, collagen IV, and...

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Detalles Bibliográficos
Autores principales: Qin, Dong, Zhang, Guo-ming, Xu, Xun, Wang, Li-ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324947/
https://www.ncbi.nlm.nih.gov/pubmed/25695094
http://dx.doi.org/10.1155/2015/920280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324947/
https://www.ncbi.nlm.nih.gov/pubmed/25695094
http://dx.doi.org/10.1155/2015/920280

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