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Sativex in the Management of Multiple Sclerosis-Related Spasticity: Role of the Corticospinal Modulation

Sativex is an emergent treatment option for spasticity in patients affected by multiple sclerosis (MS). This oromucosal spray, acting as a partial agonist at cannabinoid receptors, may modulate the balance between excitatory and inhibitory neurotransmitters, leading to muscle relaxation that is in t...

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Detalles Bibliográficos
Autores principales: Russo, Margherita, Calabrò, Rocco Salvatore, Naro, Antonino, Sessa, Edoardo, Rifici, Carmela, D'Aleo, Giangaetano, Leo, Antonino, De Luca, Rosaria, Quartarone, Angelo, Bramanti, Placido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325203/
https://www.ncbi.nlm.nih.gov/pubmed/25699191
http://dx.doi.org/10.1155/2015/656582