Activated STAT5 Confers Resistance to Intestinal Injury by Increasing Intestinal Stem Cell Proliferation and Regeneration

Intestinal epithelial stem cells (IESCs) control the intestinal homeostatic response to inflammation and regeneration. The underlying mechanisms are unclear. Cytokine-STAT5 signaling regulates intestinal epithelial homeostasis and responses to injury. We link STAT5 signaling to IESC replenishment up...

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Detalles Bibliográficos
Autores principales: Gilbert, Shila, Nivarthi, Harini, Mayhew, Christopher N., Lo, Yuan-Hung, Noah, Taeko K., Vallance, Jefferson, Rülicke, Thomas, Müller, Mathias, Jegga, Anil G., Tang, Wenjuan, Zhang, Dongsheng, Helmrath, Michael, Shroyer, Noah, Moriggl, Richard, Han, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325270/
https://www.ncbi.nlm.nih.gov/pubmed/25579133
http://dx.doi.org/10.1016/j.stemcr.2014.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325270/
https://www.ncbi.nlm.nih.gov/pubmed/25579133
http://dx.doi.org/10.1016/j.stemcr.2014.12.004

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