Inter-species inference of gene set enrichment in lung epithelial cells from proteomic and large transcriptomic datasets

Motivation: Translating findings in rodent models to human models has been a cornerstone of modern biology and drug development. However, in many cases, a naive ‘extrapolation’ between the two species has not succeeded. As a result, clinical trials of new drugs sometimes fail even after considerable...

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Detalles Bibliográficos
Autores principales: Hormoz, Sahand, Bhanot, Gyan, Biehl, Michael, Bilal, Erhan, Meyer, Pablo, Norel, Raquel, Rhrissorrakrai, Kahn, Dayarian, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Improver Challenge Special Issue; Species Translation Challenge
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325538/
https://www.ncbi.nlm.nih.gov/pubmed/25152231
http://dx.doi.org/10.1093/bioinformatics/btu569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325538/
https://www.ncbi.nlm.nih.gov/pubmed/25152231
http://dx.doi.org/10.1093/bioinformatics/btu569

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