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Inter-species inference of gene set enrichment in lung epithelial cells from proteomic and large transcriptomic datasets
Motivation: Translating findings in rodent models to human models has been a cornerstone of modern biology and drug development. However, in many cases, a naive ‘extrapolation’ between the two species has not succeeded. As a result, clinical trials of new drugs sometimes fail even after considerable...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325538/ https://www.ncbi.nlm.nih.gov/pubmed/25152231 http://dx.doi.org/10.1093/bioinformatics/btu569 |