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Mycobacterium tuberculosis epitope-specific interferon-g production in healthy Brazilians reactive and non-reactive to tuberculin skin test

The interferon (IFN)-γ response to peptides can be a useful diagnostic marker of Mycobacterium tuberculosis (MTB) latent infection. We identified promiscuous and potentially protective CD4(+ )T-cell epitopes from the most conserved regions of MTB antigenic proteins by scanning the MTB antigenic prot...

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Detalles Bibliográficos
Autores principales: da Silva, Bosco Christiano Maciel, Grassi, Maria Fernanda Rios, Coutinho, Raimundo, Mascarenhas, Rita Elizabeth Moreira, Olavarria, Viviana Nilla, Coutinho-Borgo, Adriana, Kalil, Jorge, Cunha, Edecio, Fonseca, Simone Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325617/
https://www.ncbi.nlm.nih.gov/pubmed/25494469
http://dx.doi.org/10.1590/0074-0276140193