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Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100

Apolipoprotein (apo) B is an obligatory component of very low density lipoprotein (VLDL), and its cotranslational and posttranslational modifications are important in VLDL synthesis, secretion, and hepatic lipid homeostasis. ApoB100 contains 25 cysteine residues and eight disulfide bonds. Although t...

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Detalles Bibliográficos
Autores principales: Wang, Shiyu, Park, Shuin, Kodali, Vamsi K., Han, Jaeseok, Yip, Theresa, Chen, Zhouji, Davidson, Nicholas O., Kaufman, Randal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325832/
https://www.ncbi.nlm.nih.gov/pubmed/25518935
http://dx.doi.org/10.1091/mbc.E14-08-1274