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Cytoskeletal forces during signaling activation in Jurkat T-cells

T-cells are critical for the adaptive immune response in the body. The binding of the T-cell receptor (TCR) with antigen on the surface of antigen-presenting cells leads to cell spreading and signaling activation. The underlying mechanism of signaling activation is not completely understood. Althoug...

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Detalles Bibliográficos
Autores principales: Hui, King Lam, Balagopalan, Lakshmi, Samelson, Lawrence E., Upadhyaya, Arpita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325839/
https://www.ncbi.nlm.nih.gov/pubmed/25518938
http://dx.doi.org/10.1091/mbc.E14-03-0830