Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells

Transport of insulin across the microvasculature is necessary to reach its target organs (e.g., adipose and muscle tissues) and is rate limiting in insulin action. Morphological evidence suggests that insulin enters endothelial cells of the microvasculature, and studies with large vessel–derived end...

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Detalles Bibliográficos
Autores principales: Azizi, Paymon M., Zyla, Roman E., Guan, Sha, Wang, Changsen, Liu, Jun, Bolz, Steffen-Sebastian, Heit, Bryan, Klip, Amira, Lee, Warren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325843/
https://www.ncbi.nlm.nih.gov/pubmed/25540431
http://dx.doi.org/10.1091/mbc.E14-08-1307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325843/
https://www.ncbi.nlm.nih.gov/pubmed/25540431
http://dx.doi.org/10.1091/mbc.E14-08-1307

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