The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise

Transcriptional stochasticity can be measured by counting the number of mRNA molecules per cell. Cell-to-cell variability is best captured in terms of concentration rather than molecule counts, because reaction rates depend on concentrations. We combined single-molecule mRNA counting with single-cel...

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Detalles Bibliográficos
Autores principales: Kempe, Hermannus, Schwabe, Anne, Crémazy, Frédéric, Verschure, Pernette J., Bruggeman, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325848/
https://www.ncbi.nlm.nih.gov/pubmed/25518937
http://dx.doi.org/10.1091/mbc.E14-08-1296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325848/
https://www.ncbi.nlm.nih.gov/pubmed/25518937
http://dx.doi.org/10.1091/mbc.E14-08-1296

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