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The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise
Transcriptional stochasticity can be measured by counting the number of mRNA molecules per cell. Cell-to-cell variability is best captured in terms of concentration rather than molecule counts, because reaction rates depend on concentrations. We combined single-molecule mRNA counting with single-cel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325848/ https://www.ncbi.nlm.nih.gov/pubmed/25518937 http://dx.doi.org/10.1091/mbc.E14-08-1296 |