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CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis

INTRODUCTION: CD55, a glycosylphosphatidylinositol-anchored, complement-regulating protein (decay-accelerating factor), is expressed by fibroblast-like synoviocytes (FLS) with high local abundance in the intimal lining layer. We here explored the basis and consequences of this uncommon presence. MET...

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Detalles Bibliográficos
Autores principales: Karpus, Olga N, Kiener, Hans P, Niederreiter, Birgit, Yilmaz-Elis, A Seda, van der Kaa, Jos, Ramaglia, Valeria, Arens, Ramon, Smolen, Josef S, Botto, Marina, Tak, Paul P, Verbeek, J Sjef, Hamann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325944/
https://www.ncbi.nlm.nih.gov/pubmed/25596646
http://dx.doi.org/10.1186/s13075-015-0518-4