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Local uterine Ang-(1–7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats

BACKGROUND: Endocannabinoids (ECs) are important contributors to implantation and decidualization and are suppressed in early pregnancy. Elevated levels of anandamide (AEA), the endogenous ligand for the CB1 and CB2 receptors (R), interfere with receptivity of the blastocyst. Ang-(1–7) is down-regul...

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Detalles Bibliográficos
Autores principales: Brosnihan, K Bridget, Pulgar, Victor M, Gallagher, Patricia E, Neves, Liomar AA, Yamaleyeva, Liliya M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325957/
https://www.ncbi.nlm.nih.gov/pubmed/25596750
http://dx.doi.org/10.1186/1477-7827-13-5