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Local uterine Ang-(1–7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats
BACKGROUND: Endocannabinoids (ECs) are important contributors to implantation and decidualization and are suppressed in early pregnancy. Elevated levels of anandamide (AEA), the endogenous ligand for the CB1 and CB2 receptors (R), interfere with receptivity of the blastocyst. Ang-(1–7) is down-regul...
Autores principales: | Brosnihan, K Bridget, Pulgar, Victor M, Gallagher, Patricia E, Neves, Liomar AA, Yamaleyeva, Liliya M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325957/ https://www.ncbi.nlm.nih.gov/pubmed/25596750 http://dx.doi.org/10.1186/1477-7827-13-5 |
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