Contribution of the CR Domain to P-Selectin Lectin Domain Allostery by Regulating the Orientation of the EGF Domain

The allostery of P-selectin has been studied extensively with a focus on the Lec and EGF domains, whereas the contribution of the CR domain remains unclear. Here, molecular dynamics simulations (MDS) combined with homology modeling were preformed to investigate the impact of the CR domain on P-selec...

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Detalles Bibliográficos
Autores principales: Lü, Shouqin, Chen, Shenbao, Mao, Debin, Zhang, Yan, Long, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326174/
https://www.ncbi.nlm.nih.gov/pubmed/25675100
http://dx.doi.org/10.1371/journal.pone.0118083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326174/
https://www.ncbi.nlm.nih.gov/pubmed/25675100
http://dx.doi.org/10.1371/journal.pone.0118083

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